TRP超家族与功能性胃肠病
| 作 者：耿瑞慧, 高峻, 李兆申 |
| 单 位：第二军医大学长海医院消化内科 |
| 基金项目： |
| 摘 要： |
| 摘要 功能性胃肠病（FGIDs）是消化系统常见疾病，其发病机制复杂，症状的产生涉及多种病理生理改变。瞬时受体电位（TRP）通道蛋白可通过多种机制活化，感受细胞内外环境的各种刺激，参与生物体内多种生命活动。本文就TRP超家族与FGIDs之间的联系作一综述。 |
| 关键词：瞬时受体电位通道；感受器，感觉；痛觉过敏；内脏高敏感；功能性胃肠病 |
TRP Superfamily and Functional Gastrointestinal Disorders
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| Institution: |
| Abstract: |
| Abstract Functional gastrointestinal disorders (FGIDs) are commonly seen diseases of digestive system. The pathogenesis of FGIDs is complicated and various physiologic and pathologic changes are involved in the development of symptoms of these disorders. Transient receptor potential (TRP) channel proteins can be activated by a plethora of mechanisms, receive stimulations from intracellular or extracellular environment, and participate in many kinds of vital activities in organism. In this article, the correlations between TRP superfamily and FGIDs were reviewed. |
| Keywords: Transient Receptor Potential Channels; Receptors, Sensory; Hyperalgesia; Visceral Hypersensitivity; Functional Gastrointestinal Disorders |
| 投稿时间：2009-06-01 |
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