呼气检测在消化系统疾病中应用的专家共识

作    者:中华医学会消化病学分会胃肠微生态学组, 《中华消化杂志》编辑委员会, 杨云生
单    位:北京市复兴路28号 解放军总医院消化科
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摘    要:
氢气、甲烷呼气试验已广泛应用于小肠细菌过度生长等疾病的临床诊断,我国尚无相关技术标准或临床应用指南。一氧化氮和硫化氢作为重要的气体信号分子,近年来其呼气检测在消化系统疾病中的研究和应用日益增加。中华医学会消化病学分会胃肠微生态学组和《中华消化杂志》编辑委员会组织相关专家,针对氢气、甲烷、硫化氢、一氧化氮呼气检测的方法学、适应证、临床应用等方面的研究证据,依照共识指南制定原则和方法制定此共识,针对呼气检测在成人消化系统疾病中的13个临床问题和在儿童消化系统疾病中的4个临床问题形成共21条推荐意见,为呼气检测在消化系统疾病中的规范使用提供参考依据。
关键词:呼气检测; 消化系统疾病; 氢气; 甲烷; 硫化氢; 一氧化氮

Expert Consensus on Application of Breath Test in Digestive Disorders

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Abstract:
Hydrogen and methane breath tests have been widely used in clinical detection of diseases such as small intestinal bacterial overgrowth (SIBO), yet China lacks relevant technical standards or clinical application guidelines. As important signal molecules, nitric oxide and hydrogen sulfide have appeared in increasing researches and applications in breath testing for digestive disorders in recent years. The Gut Microbiota Group of Chinese Society of Gastroenterology, Chinese Medical Association and the Editorial Board of Chinese Journal of Digestion organized experts to review research evidence on the methodology, indications, and clinical applications of hydrogen, methane, hydrogen sulfide, and nitric oxide breath testing. Following the principles and methods of consensus and guideline development, this consensus was formulated, including 21 recommendations addressing 13 clinical questions in adult digestive disorders and 4 clinical questions in pediatric gastroenterology. It aims to provide a reference for the standardized use of breath testing for digestive disorders.
Keywords: Breath Test; Digestive System Diseases; Hydrogen; Methane; Hydrogen Sulfide; Nitric Oxide
投稿时间:2026-02-13  
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